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2015-09-01 · N-oxide preparation. Sildenafil N-oxide was prepared using a variation of the procedure described in the sildenafil citrate USP monograph (2012) with 2.8 mg of sildenafil citrate dissolved in a combination of 260 μL 30% hydrogen peroxide and 130 μL anhydrous formic acid, vortex-mixed, and allowed to sit uncapped for 48 h.
CAT No: SZ-V002002. CAS No: 1622425-52-8. Mol.F. : C26H27N5O3. Mol.Wt.
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Vardenafil N-Oxide 448184-48-3. Synonyms: Vardenafil N-Oxide: Chemical Name: 1-[[3-(1,4-Dihydro-5-methyl-4-oxo-7-propylimidazo[5,1-f][1,2,4]triazin-2-yl)-4 2018-10-01 · M3 metabolite (m/z 505.2215, C 23 H 33 N 6 O 5 S) was identified as the vardenafil N-oxide. Characteristic fragment with m/z 477.1893 (C 21 H 29 N 6 O 5 S) which belong to the one of the most abundant ions in fragmentation pattern testifies to deethylation of piperazine ring with simultaneous formation of a hydroxyl group in the position 4 of piperazine. 2015-09-01 · N-oxide preparation.
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